Active Ingredients: Efavirenz 600 mg + Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg
Dosage: One a day
What is Atripla?
Atripla (efavirenz, emtricitabine, and tenofovir) is an antiviral medication that prevents human immunodeficiency virus (HIV) from reproducing in your body.
Atripla treats HIV, which causes acquired immunodeficiency syndrome (AIDS). This medication is not a cure for HIV or AIDS.
Atripla may also be used for purposes not listed in this medication guide.
Before taking Atripla
You should not take Atripla if you are allergic to efavirenz (Sustiva), emtricitabine (Emtriva), or tenofovir (Viread), or if you are taking any of the following drugs:
midazolam (Versed) or triazolam (Halcion);
St. John's wort;
an ergot medicine such as dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), ergotamine (Ergomar), or methylergonovine (Methergine);
lamivudine (Combivir, Epivir, Epzicom, or Trizivir); or
any other medicines that also contain efavirenz, emtricitabine, or tenofovir (such as Complera, Sustiva, Emtriva, Truvada, or Viread).
To make sure you can safely take Atripla, tell your doctor if you have any of these other conditions:
- liver or kidney disease;
- a history of mental illness, use of antipsychotic medication, or injection drug use;
- epilepsy or other seizure disorder;
- osteopenia (low bone mineral density); or
- hepatitis B or C infection.
FDA pregnancy category D. Do not use Atripla if you are pregnant. It could harm the unborn baby. Tell your doctor if you become pregnant during treatment. Use two forms of birth control, including a barrier form (such as a condom or diaphragm with spermicide) while you are using Atripla and for at least 12 weeks after your treatment ends. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk. Some people develop a life-threatening condition called lactic acidosis while taking Atripla. You may be more likely to develop lactic acidosis if you are overweight or have liver disease, if you are a woman, or if you have taken HIV or AIDS medications for a long time. Talk with your doctor about your individual risk.
How should I take Atripla?
Take Atripla exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
Take Atripla on an empty stomach at bedtime.
Use this medication regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
To be sure Atripla is helping your condition, your blood will need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.
If you have hepatitis B you may develop liver symptoms after you stop taking this medication, even months after stopping. Your doctor may want to check your liver function for several months after you stop using Atripla.
Atripla can cause you to have a false positive drug-screening test. If you provide a urine sample for drug-screening, tell the laboratory staff that you are taking Atripla.
HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient intructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
Store Atripla in the original container at room temperature, away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention. Overdose can cause uncontrolled muscle movements.
What should I avoid while taking Atripla?
Drinking alcohol can increase certain side effects of Atripla. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Taking Atripla will not prevent you from passing HIV to other people. Avoid having unprotected sex or sharing razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.